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Retina Observation for Alzheimer Diagnostic


The ROAD to the early detection of neurodegenerative diseases

The primary goal of the ROAD project is the development of a novel device for the early detection and continuous monitoring of specific neurodegenerative pathologies, including Alzheimer's disease and Parkinson's disease, through in-vivo observation of the human retina at high-resolution.

LinkedIn

29 October 2025

📸 Sharing science across conferences!
We are proud of our team members @silvia di angelantonio, @Alberto Boffi and @giancarlo ruocco, who recently joined two international events in China: JAR Innovation and Enterprise Cooperation Forum (Keqiao Series IV) at @Keqiao International Park and @Advanced Materials International Conference 2025

🎙️ In their keynote speeches, Silvia and Alberto presented preliminary results from our ROAD project, focusing on the formulation and characterization of functionalized ferritin-based nanocages loaded with a specific Tau protein ligand.

A great opportunity to strengthen collaborations 🤝 and share knowledge within the scientific community 🌍

Conference Research Dissemination ScienceCommunication 

28 October 2025

🧬 Organoids: a promising alternative to animal testing 📰

🎤 Trend Sanità interviewed @silvia di angelantonio, who shares how in the ROAD project we are using brain and retinal organoids to gain deeper insights into neurodegenerative diseases characterized by tau protein aggregation and to develop specialized probes for early diagnosis.

These patient-derived models help us reduce (though not completely replace) animal testing and build disease models closer to human biology, paving the way for a more innovative, ethical, and patient-tailored science.

🔗 Read the full interview here 
https://lnkd.in/gmmeBUjx

Research Organoids Neurodegeneration Innovation ROADproject

22 October 2025

📢 Our ROAD project, led by Giancarlo Ruocco at @Istituto Italiano di Tecnologia and @D-Tails Research, has been featured in national media — including @ANSA! 📰

👏 Our research has been awarded over €3 million from @Ministero Istruzione, Universita' e Ricerca (MUR) to pave the way for the early detection of neurodegenerative diseases.

🔗 Read more about it here: https://lnkd.in/dJwm5-8g

Research Neuroscience Innovation MUR ScienceNews

06 September 2025

https://giornaleradio.fm/

🎙️Vi ricordiamo l’intervista a @silvia di angelantonio durante il programma Cosmo2050 in onda fra poco (ore 14:00)… non perdetevela! 🎙️

@Istituto Italiano di Tecnologia @D-Tails Research

ROADproject IIT interview research

05 September 2025

🧠✨ Nuove prospettive nella cura della demenza frontotemporale, offerte dall'utilizzo del farmaco bezafibrato, comunemente usato per abbassare il colesterolo.

Questo sarà l'oggetto dell'interessante intervista a @silvia di angelantonio durante il programma Cosmo2050 su @Giornale Radio,
🎙️ in onda sabato 6 Settembre 2025 alle 14:00. 🎙️

📖 Si parlerà dei risultati della ricerca appena pubblicati sulla rivista Alzheimer’s & Dementia \@alzdemjournal, nel paper intitolato "Bezafibrate treatment rescues neurodevelopmental and neurodegenerative defects in 3D cortical organoid model of MAPT frontotemporal dementia".
Lo studio è stato coordinato da @silvia di angelantonio, in collaborazione con \@Paola Bezzi (@Sapienza Università di Roma e Università di Losanna), ed è parte del progetto @ROAD Project in collaborazione con @D-Tails Research.

👉 Non perdete l'intervista!

RadioInterview Neuroscience FrontotemporalDementia Research ROADproject

05 September 2025

✨ New Publication Alert! ✨
We are glad to share that a new scientific article related to our project ROAD has just been published in Alzheimer’s & Dementia (\@alzdemjournal).


👉 You can read the full paper here: https://lnkd.in/dwsB4-NN

We are proud of this achievement and of the collaboration that made it possible, and we look forward to sharing further updates as our research progresses.

Research Publication Science Innovation Teamwork ROADproject

08 August 2025

🚀 The official website of the ROAD project is now online! 🌐

From project goals to research highlights, news, and events, you’ll find everything you need to follow our journey.
@D-Tails Research & CLN2S of @Istituto Italiano di Tecnologia
🔗 Link in the comments

More updates coming soon—stay connected!

Research Science Innovation ROADproject TeamWork

23 June 2025

✨ Welcome to the ROADproject - Retina Observation for Alzheimer Diagnostic - coordinated by @giancarlo ruocco at @Istituto Italiano di Tecnologia together with @D-Tails Research, focused on developing a novel device for early detection and continuous monitoring of specific neurodegenerative diseases.

On June 10th, we successfully held the 🚀 ROAD kick-off meeting, marking the beginning of this promising journey!
The event brought together all project partners and their teams, to align on objectives, work plans, and collaboration strategies for the upcoming phases.
Looking forward to what’s next – stay tuned for more updates! 👀

KickOffMeeting NewProject Neurodegeneration Optics Innovation DtailsResearch IIT